ghrelin improves rat sperm kinematic parameters during abdominal position of the testis

نویسندگان

arash kheradmand

چکیده

background: disruption of testicular function and arrest ofspermatogenesis are the consequence of cryptorchidism inresponse to elevated temperature. objectives:this investigationwas set to clarify the possible ghrelin efficacy in altering somesperm quality parameters upon experimentally-induced cryptorchidism.methods: thirty male adult rats were scheduled for thestudy and were divided into three groups: group 1 was served ascontrol-saline (cs), group 2 was designed as cryptorchidism-saline(crs), and group 3 was defined as cryptorchidism-ghrelin (crg).after surgically inducing cryptorchidism in groups 2 and 3, theresearchers gave 10 nmol of ghrelin to crg rats for 7 consecutivedays. five animals in each group were equally killed on days 3 and7 after operation and their testes were taken for sperm evaluation.results: testicular weight, sperm forward progressive motility(fpm), functional membrane integrity (assessed by hos-test), andsperm concentration displayed slight changes after heating on day3. however, abdominal position of the testes for 7 days caused asignificant reduction in the percentages of hos-positive cells(p

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عنوان ژورنال:
iranian journal of veterinary medicine

ناشر: دانشگاه تهران

ISSN 2251-8894

دوره 8

شماره 2 2014

کلمات کلیدی

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